Toxic epidermal necrolysis (TENS) is a severe form of Stevens-Johnson syndrome.

These rare disorders affect the skin and mucous membranes, causing the skin to blister and detach. TENS is typically caused when someone has a severe reaction to a medication or infection.

The symptoms resemble those associated with a burn injury, including blistering of the skin, a burning sensation, redness and peeling of the skin. Early signs of TENS may include fever, flu-like illness, eye itching and burning, joint pain and cough. Later, the patient may develop patches of painful red/purple skin with peeling blisters, which are often painful. This may affect the mucosal lining, such as the inside of your mouth, lips, windpipe, lungs and gastrointestinal tract. Symptoms may include sores on the lining of the mouth, eyes and genitals, as well as difficulty breathing. When a patient's skin is sloughed off, their body is unprotected from surrounding infections and bacteria. Patients may also not be able to take in enough nutrition and fluid on their own.

When traumatic wounds or blistering skin diseases become serious, get infected or fail to heal, Shriners Children’s has experienced staff to help contribute to better outcomes. Shriners Children’s offers innovative treatments such as skin grafting and specialized wound care.

Treatment for very severe toxic epidermal necrolysis can be like that developed for burn wounds. Shriners Children’s uses advanced burn care and plastic surgery techniques to save skin tissue, reduce the risk of infections, and provide the best appearance for patients.

Children with very severe cases of TENS are likely to end up in a burn unit, where the critical care and wound management expertise of our staff can be applied to the organ failures and wounds seen in children with severe TENS.
Robert L. Sheridan, M.D., Shriners Children’s Boston Chief of Staff and Director of the Burn Service

Wound Care and Skin Disorders

Shriners Children’s medical staff treat various wounds and skin disorders through surgical and non-surgical techniques to correct skin differences. Through the help of the Shriners Children’s, our team supports the self-esteem of each child to help them reach their dreams and goals.

Innovative Treatments

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Atención de quemaduras

Shriners Children's ofrece tratamiento para quemaduras de todo grado y tipo, incluidas quemaduras químicas, quemaduras por la electricidad y quemaduras por llamas. Nuestros planes de tratamiento personalizados de atención de quemaduras pediátricas pueden incluir cuidado de las heridas, tratamiento de cicatrices y reconstrucción.

Cirugía plástica

Los experimentados cirujanos plásticos pediátricos de Shriners Children's emplean técnicas de cirugía plástica reconstructiva que brindan esperanza y rehabilitación a las familias que enfrentan diferencias que afectan el rostro, la mandíbula, los párpados, las orejas, las mamas o la piel.

Injerto de piel

En Shriners Children's, mejoramos el tratamiento y la curación de niños con quemaduras. Cuando una parte del cuerpo pierde su capa protectora, podemos realizar un injerto de piel, que es un trasplante de piel de una zona del cuerpo a otra.

Next Steps

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